Organic Tea Tree Oil
tea tree oil from melaleuca*alternifolia
CAS: 68647-73-4
Molecular Formula:
Organic Tea Tree Oil - Names and Identifiers
Organic Tea Tree Oil - Physico-chemical Properties
| Density | 0.878g/mLat 25°C(lit.) |
| Melting Point | EU Regulation 1334/2008 & 872/20 |
| Boling Point | 165°C(lit.) |
| Specific Rotation(α) | D +6°48 to +9°48 |
| Flash Point | 147°F |
| Appearance | liquid |
| Merck | 13,9175 |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.478(lit.) |
| MDL | MFCD00132409 |
Organic Tea Tree Oil - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | RJ3697600 |
| Toxicity | LD50 orally in rats: 1.9-2.6 ml/kg; dermally in rabbits: 5.0 g/kg (Halcón) |
Organic Tea Tree Oil - Introduction
Strong camphor gas and bitter taste.
Last Update：2022-10-16 17:27:55
Organic Tea Tree Oil - Reference Information
| FEMA | 3902 | TEA TREE OIL |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | tea tree essential oil is extracted from tea plant (Melaleuca alternifolia), is one of the most commonly used essential oils. It is one of the most effective essential oils to improve body immunity, can treat sudden Virus, bacterial and fungal infections, clean wounds, relieve muscle soreness symptoms. |
| Main components | The main components of tea tree essential oil are: phenethyl alcohol, ethanol, benzaldehyde, citronellol, geraniol, n-butyraldehyde, isobutyraldehyde, acetic acid, hexanoic acid, etc. |
| Use | as a natural disinfectant, tea tree oil is widely used in the prevention and treatment of various diseases, especially aromatherapy, such as abscesses, facial cells, acne, acne, athlete's foot, nail infections, blisters, burns, frostbite, sunburn, dandruff, money, insect bites, rashes, warts, infected wounds and other skin problems, such as otitis, gum inflammation, stomatitis, bronchitis, asthma, pharyngitis, throat mucositis, Cough, sinusitis, tuberculosis, asthma Cough and other ear nose and throat and respiratory organs of the official face of the disease, such as vaginitis, vaginal itching, cystitis, anal fissure and other reproductive in the urinary tract infection, such as cold, cold, fever, influenza, treatment of glandular Fever, infectious diseases and systemic problems that enhance immune function in AIDS patients. |
| application field | 1. Application of tea tree oil in cosmetics tea tree oil is widely used in many fields because it contains a variety of active ingredients, especially in cosmetics and daily chemicals. Mainly used in acne cream, acne cream, in addition to the stain and age spots in cosmetics. 2. Application of tea tree oil in medicine according to the study, the main component of tea tree oil terpinol-4 has a strong antibacterial effect on Staphylococcus aureus, Staphylococcus epidermidis, Beta hemolytic Streptococcus, Escherichia coli, pseudomonas aeruginosa and Candida albicans have strong antibacterial properties, so it is an excellent natural antibacterial agent. Tea tree oil is of great help in the treatment of many diseases and wounds, such as cuts, abrasions, bites by insects, acne, burns, vaginal infections and ringworm. 3. The application of tea tree oil in food in food, tea tree oil is used as a kind of flavor, become a kind of fresh and distinctive taste. |
| function | 1. Tea tree oil as a potential natural food antibacterial preservative, compared with the chemical synthesis of preservatives, tea tree oil has unique advantages: (1) pure natural, environmental protection; (2) high antibacterial activity, it still has a killing effect on drug-resistant bacteria, and has few factors affecting sterilization. ③ non-toxic, harmless, small, no residue, in line with the social development direction of "green life, energy saving and environmental protection. It has been reported that tea tree oil is used in the field of food preservation. Try as a new preservative for banana and strawberry preservation. The study on the mechanism of tea tree oil sterilization is still in its infancy, and there is no clear way and method. Liposome studies have shown that terpenes have the ability to disrupt and penetrate lipid structures. Aromatic Hydrocarbons and terpenes accumulate in the lipid bilayer of the cell membrane, affecting the structure and function of the membrane, causing the membrane to lose integrity, increasing the permeability of the substance and ions, causing the proton kinetic potential to dissipate due to intracellular changes, cause intracellular damage, lipophilic compounds on the membrane protein embedded in the membrane lipid part of the role, the role of membrane proteins may cause a large degree of changes in the lipid environment, outer membrane lipopolysaccharide changes, changes in cell wall composition. Tea tree oil and its components act on microbial cell membranes to form perforations, so that cell contents, especially potassium ions, leak out in large quantities, disrupting the normal distribution of lipid molecules in the cell membrane bilayer structure, and inducing hydrolytic enzymes that degrade cell walls to stimulate cell autolysis, action on normal cell membrane depolarization leads to cell death, resulting in increased sensitivity of cells to sodium chloride, inhibition of respiration, The morphological changes of the cells, the loss of absorbing substances, the formation of interstitial cells and the loss of cytoplasm were observed by electron microscopy, which indicated that the cell membrane was destroyed after the treatment with tea tree oil. Based on these data, it is believed that the tea tree oil kills microorganisms in a manner similar to a membrane active disinfectant. As a membrane active disinfectant, tea tree oil can kill many different microorganisms. Because the tea tree oil contains a variety of components, the content of each component is different, the solubility and molecular weight are different, so the physical and chemical properties are different, and the rate of penetration through the cell wall and cell membrane structure is also different. In addition, the antibacterial activity of the tea tree oil may exist at sites of action other than the membrane or unknown components in the tea tree oil, as well as other mechanisms of bactericidal action. 2. Anti-Virus activity of tea tree oil the anti-Virus activity of tea tree oil was first found in the resistance test to tobacco mosaic Virus. On this basis, the researchers used eucalyptus oil as a control to study the inhibitory effect of tea tree oil on the formation of herpes simplex Virus type 1 and type 2. The final results showed that tea tree oil inhibited the formation of herpes simplex Virus 50%, the change in concentration was also found to have a significant effect on the Virus inhibition. In addition, the effect of tea tree oil on Virus in the free period was the most significant. Since then, it has been discussed whether tea tree oil can effectively inhibit influenza Virus induced dog kidney cells (MDCK), the results show that when the dose is less than the cytotoxic dose, tea tree oil can significantly inhibit the apoptosis induced by influenza A Virus A/PR/8/34. It can be seen that the tea tree oil can act on the envelope and non-envelope Virus, but the Virus species reported so far are few. 3. Anti-inflammatory activity of tea tree oil tea tree oil can inhibit the production of superoxide and pro-inflammatory mediators in human monocytes, it will reduce the production of inflammation, while it will not affect the secretion of anti-inflammatory factors and the production of cells. Studies have shown that tea tree oil can significantly inhibit necrosis factor, which can effectively protect cells. There are also clinical experiments show that tea tree oil can inhibit the human skin to get the wind and erythema and other inflammation. 4. Other tea tree oil in the inhibition of mites have also been studied, it can reduce the survival time of scabies mites, but not all components of tea tree oil can inhibit the growth of mites, only terpinen-4-ol has a significant effect. In the aspect of tumor, the tea tree oil has obvious inhibitory effect on the tumor cells of liver cancer cells, cervical cancer cells and leukemia cells, and the main way is to inhibit the apoptosis of tumor cells. In real life, tea tree oil has a cough effect, mainly can treat Cough of the response caused by capsaicin, the active ingredient is terpinen-4-ol. Tea tree oil also has antioxidant activity, mainly has a strong ability to scavenge free radicals, so tea tree oil can be used as a natural antioxidant. |
| extraction process | generally, tea tree essential oil is usually extracted by distillation, solvent extraction and microwave-assisted solvent extraction. Distillation is divided into water distillation, water distillation, steam distillation 3. Steam distillation is often used to extract tea tree oil in industrial production. But for fresh or dried Melaleuca alternifolia branches and leaves, the yield of essential oil had no obvious difference. The oil yield of solvent extraction (using ethanol as solvent) is often higher than that of water gas distillation (10% ~ 20%). The yield of monoterpene compounds can be increased by 4% ~ 6%, and the yield of sesquiterpene compounds is more obvious. Since the solvent extraction method does not change the composition of the essential oil, and is more in line with the composition of the essential oil in the branches and leaves, the solvent extraction method is commonly used in the comparison and screening of plant varieties (such as for variety breeding). |
| recommended use | tea tree essential oil is transparent in color and extremely low in viscosity. If it drops on the surface, it can volatilize within 24 hours, and no trace was left. General skin no irritation, but such as the use of drugs on the skin, excessive use of cosmetics and detergents lead to the fragility of the skin, then if the use of 100% purity of the tea tree, may cause skin sensitivity. Although the tea tree is non-toxic, it is absolutely not recommended to take pure tea tree essential oil orally. The effect of tea tree is also external rather than internal use, and the oral use is not beneficial. |
| method of use | Direct Use: Method 1: severe acne, take pure tea tree essential oil with a cotton swab and gently point it on the acne, anti-bacterial anti-inflammatory convergence of the role of acne. Harmonic use: Method 1: 1-2 drops of tea tree essential oil applied to the face mask for 15 minutes. Suitable for oily skin, large pores of the conditioning. Method 2: 3 drops of tea tree essential oil, 2 drops of rosemary essential oil, 5 ml of grape seed oil, do facial detoxification massage, and then use a clear face to clean, and then spray tea tree flower water. Method 3: 1 drop of pure tea tree essential oil was dripped into 10 grams of cream/emulsion/toner and mixed evenly to condition acne skin and balance oil secretion. |
| preparation | (1) weigh 100g of fresh branches and leaves of Melaleuca alternifolia, add 200g of n-hexane, and put them into microwave reactor, install the condenser tube;(2) set the microwave power to 800W, the temperature to 40 ℃, each microwave radiation extraction 5s, after cooling carefully poured out the supernatant, then add the appropriate amount of n-hexane extraction 5 times;(3) the extracts obtained in step (2) are combined and concentrated under reduced pressure with a rotary evaporator to obtain a crude product of tea tree oil essential oil, it was frozen in a refrigerator at -15 ° C. For 48h, centrifuged to remove flocculent impurities, filtered, and the filtrate was concentrated under reduced pressure with a rotary evaporator to obtain the essential oil of tea tree oil. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 21:21:28
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